参考文献 References Alfaxan

  1. Pasloske, K., et al., A multicentre clinical trialevaluating the efficacy and safety of Alfaxan® CDRTU administered to dogs for induction andmaintenance of anaesthesia. in British Small AnimalVeterinary Association Congress. 2005.Birmingham, UK.
  2. Pasloske, K., et al., A multicentre clinical trialevaluating the efficacy and safety of Alfaxan® CDRTU administered to cats for induction andmaintenance of anaesthesia. in British Small AnimalVeterinary Association Congress. 2007.Birmingham, UK.
  3. Jurox, Jurox Pharmacovigilance reportJX9604-SR004. 2005.
  4. Muir, W., et al., The cardiorespiratory and anestheticeffects of clinical and supraclinical doses ofalfaxalone in cats. Veterinary Anaesthesia andAnalgesia, 2009. 36(1) : p.42-54
  5. Muir, W., et al., Cardiorespiratory and anestheticeffects of clinical and supraclinical doses ofalfaxalone in dogs. Veterinary Anaesthesia andAnalgesia, 2008. 35(6) : p.451-462.
  6. Heit, M.C., et al., Safety and efficacy of Alfaxan® CDRTU administered once to cats subcutaneously at10mg/kg. in ACVIM, 2004.
  7. Schnell, M., et al. Margin of safety of the anestheticAlfaxan® CD RTU in dogs at 0,1,3 and 5X theintravenous dose of 2mg/kg. in ACVIM. 2004.
  8. Jurox and Ricera, An in vitro study evaluating thebinding of alfaxalone to various nuclear receptors(Ricera Study No. AA94464). Records in House,2010.
  9. Jurox and Ricera, An in vitro study evaluating thebinding of alfaxalone to various abuse receptors(Ricera Study No. AA94047). Records in House,2010.
  10. Roth, F.C. and A. Draguhn, GABA Metabolism andTransport: Effects on Synaptic Efficacy. NeuralPlasticity, 2012.
  11. Selye, H., Anaesthetic effects of steroid hormones.Proceedings of the Society for ExperimentalBiology, 1941. 46 : p.116-121
  12. Phillipps, G.H., Structure-activity relationships insteroidal anaesthetics. J. Steroid Biochem., 1975. 6(5) : p.607-613
  13. Child K.J., et al., The pharmacological properties in animals of CT1341-a new steroid anaesthetic agent. Br. J. Anaesth., 1971. 43(1) : p.2-13
  14. Krantz, J.C. et al., XXVI. Pharmacodynamic studiesof polyoxyalkylene derivatives of hexitol anhydridepartial fatty acid esters. J. Pharmacol. Exp. Ther.,1948. 93(2) : p.188-195
  15. Brewster, M.E. et al., Development of anon-surfactant formulation for alfaxalone throughthe use of chemically-modified cyclodextrins.J. Parenter. Sci. Technol., 1989. 43(6) : p.262-5
  16. Brewster, M.E., et al., An intravenous toxicity studyof 2-hydroxypropyl-β-cyclodextrin, a useful drugsolubilizer, in rats and monkeys.Int. J. Pharm., 1990. 59 : p.231-243
  17. Child, K.J., et al., Metabolism and excretion ofAlthesin (CT1341) in the rat. in SteroidAnaesthesia, 1972. Postgrad. Med. J., London.
  18. Pasloske, K., JX9604.03-C009 A multi-centreclinical trial in dogs evaluating the efficacy andsafety of Alfaxan®-CD RTU administered toveterinary patients for induction and maintenanceof anaesthesia [Study Report]. 2005. Jurox PtyLimited.
  19. Pasloske, K., JX9604.07-C006 A multi-centreclinical trial in cats evaluating the efficacy andsafety of Alfaxan®-CD RTU administered toveterinary patients for induction and maintenanceof anaesthesia [Study Report]. 2005. Jurox PtyLimited.
  20. O'Hagan, B., et al., Clinical evaluation of alfaxaloneas an anaesthetic inducton agent in dogs less than12 weeks of age. Australian Veterinary Journal,2012. 90 [9] : p.346-50
  21. Pasloske, K., et al., Plasma pharmacokinetics ofalfaxalone in both premedicated andunpremedicated Greyhound dogs after single,intravenous administration of Alfaxan® at a clinicaldose. Journal of Veterinary Pharmacology andTherapeutics, 2009. 32 : p.510-513.
  1. Metcalfe, S., et al., A multi-centre clinical trialevaluating the efficacy and safety of Alfaxan®administered to bitches for induction of anaesthesiaprior to caesarean section. In 33rd World SmallAnimal Congress. 2008. Dublin, Ireland:WSAVA/FECAVA.
  2. Pasloske, K. and Whittem, T., JX9604.07-H004.  A target animal safety study in cats afteradministration of Alfaxan® CD RTU as single,repeated injections on days 0,2 and 5 at doses of 5,15 or 25mg/kg. 2004, 0n file at Jurox Pty Ltd.
  3. O'Hagan, B., et al., Clinical evaluation of alfaxaloneas an anaesthetic induction agent in cats less than12 weeks of age. Australian Veterinary Journal,2012. 90 [10] : p.395-401
  4. APVMA, Alfaxan® Anaesthetic Injection AustralianProduct Insert Leaflet. 2010
  5. Baron Strategic Services. Anaesthesia MarketResearch. Jurox vet survey report Oct 11. On file atJurox Pty. Ltd., Rutherford, NSW. Australia.
  6. Whittem, T. and Pasloske, P., RD9604.03-H005.Eight day target animal safety study of intravenousAlfaxan® CD RTU in dogs administered every otherday. 2004, Jurox Pty. Ltd.
  7. Ambros, B., et al., Comparison of the anestheticefficacy and cardiopulmonary effects of continuousrate infusions of alfaxalone-2-hydroxypropyl-β-cyclodextrin and propofol indogs. Am J vet. Res., 2008. 69(11) : p.1391-8
  8. Heit, M.C., et al., Cardiovascular and respiratorysafety of Alfaxan® CD RTU in cats premedicatedwith acepromazine, medetomidine, midazolam orbutorphanol. In ACVIM. 2004.
  9. Amengual, M., et al., An evaluation of anaestheticinduction in healthy dogs using rapid intravenousinjection of propofol or alfaxalone. VeterinaryAnaesthesia and Analgesia, 2013. 40 : p.115-123
  10. Herbert, G.L., et al., Alfaxalone for total intravenousanaesthesia in dogs undergoingovariohysterectomy : a comparison of premedicationwith acepromazine or dexmedetomidine. VeterinaryAnaesthesia and Analgesia, 2013. 40 : p.124-133
  11. Jansen, K.S. and J.J. Uilenreel, A comparisonbetween alfaxalone and propofol continuous rateinfusions in a total intravenous anaesthesia protocolfor canine surgical patients. 2009, Faculty ofVeterinary Medicine University of Utrecht.
  12. Jimenez, C.P., et al., Evaluation of the quality of therecovery after administration of propofol oralfaxalone for induction of anaesthesia in dogsanaesthetized for magnetic resonance imaging.Veterinary Anaesthesia and Analgesia, 2012. 39(2):p.151-159.
  13. Maddern, K., et al., Alfaxalone induction dosefollowing administration of medetomidine andbutorphanol in the dog. Veterinary Anaesthesia andAnalgesia, 2010. 37(1) : p.7-13.
  14. Martinez Taboada, F. and P.J. Murison, Induction ofanaesthesia with alfaxalone or propofol before isoflurane maintenance in cats. Veterinary Record,2010. 167(3) : p.85-89.
  15. Mathis, A., et al., Comparison of quality of recoveryfrom anaesthesia in cats induced with propofol oralfaxalone. Veterinary Anaesthesia and Analgesia,2012. 39(3) : p.282-290.
  16. Murison, P.J. and F. Martinez Taboada, Effect ofpropofol and alfaxalone on pain afterovariohysterectomy in cats. Veterinary Record,2010.166(11) : p.334-335.
  17. Psatha, E., et al., Clinical efficacy andcardiorespiratory effects of alfaxalone, ordiazepam/fentanyl for induction of anaesthesia indogs that are a poor anaesthetic risk. VeterinaryAnaesthesia and Analgesia, 2011. 38 : p.24-36.
  18. Zaki, S., et al., Clinical evaluation of Alfaxan-CD® asan intravenous anaesthetic in young cats.Australian Veterinary Journal, 2009. 87(3) : p.82-87.